The ESCRT machinery: new functions in viral and cellular biology.
نویسندگان
چکیده
The ESCRT (endosomal sorting complex required for transport) machinery consists of a number of cytosolic proteins that make up three functional subcomplexes: ESCRT-I, ESCRT-II and ESCRT-III. These proteins function in multivesicular body formation and cell division and are co-opted by enveloped retroviruses to facilitate viral egress. Analysis of these functions may help illuminate conserved mechanisms of ESCRT function.
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ورودعنوان ژورنال:
- Biochemical Society transactions
دوره 37 Pt 1 شماره
صفحات -
تاریخ انتشار 2009